The curiosity that started it all

Most of what makes us who we are isn’t encoded in our genes. Genes account for only 2 percent of our DNA.

The remaining 98 percent - the epigenome - determines which genes switch on, when and where they switch on, and how that regulation breaks down in disease.

Understanding disease means understanding epigenomic regulation. But today’s tools only capture fragments of the epigenome.

Researchers need technologies that work together to give a complete, coherent view of gene regulation in real samples, at real scale.

How it evolved into NEXUS

NEXUS is building a unified platform to profile the major layers of the epigenome - DNA methylation, histone modifications, and regulatory chromatin - in a versatile, accessible, plug-and-play format.

Each of our technologies will target a different layer of gene regulation, and are designed to work across bulk, single-cell, and spatial contexts, giving researchers a clear and comprehensive picture of how cells behave in health and disease.

Our platform enables scientists to explore regulatory biology with the simplicity and speed they expect from modern sequencing tools, without compromising depth or quality.