FAQs

1. What are the main benefits/advantages of using MeTLAND?

MeTLAND is a fast, user-friendly DNA methylation workflow that fits into any standard molecular biology lab.

It requires no harsh chemicals or specialized equipment and preserves DNA integrity throughout the process.

Key advantages:

> Requires only ~30M reads for high-quality data

> Rapid library preparation with minimal hands-on time

> Enables discovery-driven analysis with high-complexity libraries

2. What are the current offerings at NEXUS Epigenomics?

MeTLAND Early Access Program launched in Q4 2025 for selected researchers to benchmark our chemistry.

MeTLAND DNA Methylation Kits scheduled for release in Q1 2026.

3. What types of samples can be used with MeTLAND?

MeTLAND works across a wide range of inputs including cell lines, primary cells, nuclei suspensions, fresh or frozen tissues. We are also optimizing compatibility with FFPE (formalin-fixed, paraffin-embedded) samples.

4. What is the minimum starting material needed for MeTLAND?

Cell suspensions: 200,000 – 250,000 cells.

Tissues: Varies with complexity, rigidity, and density; as a general guide, start with ~100-150 mg.

5. What is the cost?

Please contact us for current pricing.

We offer competitive pricing tailored to project size, sample volume, and workflow needs.